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GI Cancers

Gastro-Intestinal Oncology & HPB DMG deals with malignancies related to the Gut/Intestine, Liver, Stomach, Pancreas, Gall Bladder, Oesophagus, Colon, Rectum, Anus, Bile Duct etc. The cancer can form a mass or ulcer within the stomach or it can spread diffusely throughout the entire wall of the stomach. Stomach cancer is also called gastric cancer. Stomach cancer is commonly found in people aged between 50 and 70 years of age. It is more common in men. Treatment options that are available for treating gastrointestinal cancers are Surgery, Radiotherapy, and Chemotherapy. Symptoms Symptoms of gastrointestinal cancer vary, depending on the type of cancer. Symptoms may include: Abdominal pain and discomfort Change in bowel habits Rectal bleeding Bloating Loss of appetite Nausea and vomiting Unusual weight loss Causes Smoking Too much alcohol consumption Age High animal fat diet High amount of salt intake Chronic pancreatitis Obesity

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Myeloma Cancers

Multiple myeloma is a cancer that forms in a type of white blood cell called a plasma cell. Healthy plasma cells help you fight infections by making antibodies that recognize and attack germs. In multiple myeloma, cancerous plasma cells accumulate in the bone marrow and crowd out healthy blood cells. Rather than produce helpful antibodies, the cancer cells produce abnormal proteins that can cause complications. Treatment for multiple myeloma isn’t always necessary right away. If the multiple myeloma is slow growing and isn’t causing signs and symptoms, your doctor may recommend close monitoring instead of immediate treatment. For people with multiple myeloma who require treatment, a number of options are available to help control the disease. Symptoms Signs and symptoms of multiple myeloma can vary and, early in the disease, there may be none. Bone pain, especially in your spine or chest Nausea Constipation Loss of appetite Mental fogginess or confusion Fatigue Frequent infections Weight loss Weakness or numbness in your legs Causes Doctors know that myeloma begins with one abnormal plasma cell in your bone marrow the soft, blood-producing tissue that fills in the center of most of your bones. The abnormal cell multiplies rapidly. Because cancer cells don’t mature and then die as normal cells do, they accumulate, eventually overwhelming the production of healthy cells. In the bone marrow, myeloma cells crowd out healthy blood cells, leading to fatigue and an inability to fight infections. The myeloma cells continue trying to produce antibodies, as healthy plasma cells do, but the myeloma cells produce abnormal antibodies that the body can’t use. Instead, the abnormal antibodies build up in the body and cause problems such as damage to the kidneys. Cancer cells can also cause damage to the bones that increases the risk of broken bones.

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Acute Leukemia

Acute lymphocytic leukemia (ALL) is a type of cancer of the blood and bone marrow the spongy tissue inside bones where blood cells are made. The word “acute” in acute lymphocytic leukemia comes from the fact that the disease progresses rapidly and creates immature blood cells, rather than mature ones. The word “lymphocytic” in acute lymphocytic leukemia refers to the white blood cells called lymphocytes, which all affects. Acute lymphocytic leukemia is also known as acute lymphoblastic leukemia. Acute lymphocytic leukemia is the most common type of cancer in children, and treatments result in a good chance for a cure. Acute lymphocytic leukemia can also occur in adults, though the chance of a cure is greatly reduced. Symptoms Bleeding from the gums Bone pain Fever Frequent infections Frequent or severe nosebleeds Lumps caused by swollen lymph nodes in and around the neck, armpits, abdomen or groin Pale skin Shortness of breath Weakness, fatigue or a general decrease in energy Causes Acute lymphocytic leukemia occurs when a bone marrow cell develops changes in its genetic material or DNA. A cell’s DNA contains the instructions that tell a cell what to do. Normally, the DNA tells the cell to grow at a set rate and to die at a set time. In acute lymphocytic leukemia, the mutations tell the bone marrow cell to continue growing and dividing. When this happens, blood cell production becomes out of control. The bone marrow produces immature cells that develop into leukemic white blood cells called lymphoblasts. These abnormal cells are unable to function properly, and they can build up and crowd out healthy cells. It’s not clear what causes the DNA mutations that can lead to acute lymphocytic leukemia.

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